OSISA has structured its work along six strategic thematic areas as follows:

The two “building-block” programmes of Education and Information and Communication Technologies (ICTs);

The two frontline rights programmes of Human Rights and Democracy Building (HRDB) and Media; and –

The two public policy programmes of Economic Justice and HIV and AIDS.

In addition, Language Rights and Gender and Women’s Rights are cross-cutting themes in all of OSISA’s work.